Endocrine Abstracts

Background: Age-associated double negative (DN) B memory cells lacking surface expression of CD27 and IgD have been associated with proinflammatory characteristics, higher disease activity in autoimmune diseases and disease-specific autoantibodies. We studied the distribution of DN B cells in Polycystic Ovary Syndrome (PCOS), their surface markers and cytokine production.Methods: CD19+ cell subpopulations on the basis of IgD and CD27 expression were phen...